Newborn Lamb as a New Model for Studying Gastroesophageal Reflux

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Newborn lamb as a new model for studying gastroesophageal reflux.

We aimed to determine whether the newborn lamb at term is a valid model for studying gastroesophageal reflux. Seven bottle-fed lambs, ages 2 to 3 days, underwent esophageal multichannel intraluminal impedance-pH monitoring (MII-pH). A total of 196 reflux episodes were recorded, including 73% alkaline and 27% weakly acidic. No acid refluxes were observed. Median bolus clearance time was 4  secon...

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ژورنال

عنوان ژورنال: Journal of Pediatric Gastroenterology & Nutrition

سال: 2012

ISSN: 0277-2116

DOI: 10.1097/mpg.0b013e318263cae0